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By Paul H. Sugarbaker MD, FACS, FRCS (auth.), Santiago González-Moreno MD, PhD (eds.)

S. González-Moreno (Ed. ) Advances in Peritoneal floor Oncology With forty five Figures in fifty seven Separate Illustrations, 12 in colour and 19 Tables 123 IV Preface Santiago González-Moreno, MD, PhD division of Surgical Oncology Centro Oncológico MD Anderson foreign España Calle Gómez Hemans 2 28033 Madrid Spain sgonzalez@mdanderson. es Library of Congress regulate quantity: 2006937141 ISSN 0080-0015 ISBN 978-3-540-30759-4 Springer Berlin Heidelberg long island This paintings is topic to copyright. All rights are reserved, no matter if the full or a part of the cloth is anxious, speci? ?cally the rights of translation, reprinting, reuse of illustrations, recitations, broadcasting, replica on micro? ?lm or in the other method, and garage in facts banks. Duplication of this book or components thereof is authorized merely lower than the provisions of the German Copyright legislation of September nine, 1965, in its present model, and permission to be used should always be bought from Springer-Verlag. Violations are answerable for prosecution less than the German Copyright legislation. Springer is a part of Springer Science+Business Media http//www. springer. com Springer-Verlag Berlin Heidelberg 2007 published in Germany using basic descriptive names, emblems, and so on. during this book doesn't suggest, even within the absence of a speci? ?c sta- ment, that such names are exempt from the proper protecting legislation and laws and consequently unfastened for common use. Product legal responsibility: The publishers can't warrantly the accuracy of any information regarding dosage and alertness contained during this e-book. In each case the person needs to money such details through consulting the proper literature.

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Skipper D, Cooper AJ, Marston JE, Taylor I (1987). Exfoliated cells and in vitro growth in colorectal cancer. Br J Surg 74:1049–1052 3 Pathological Evaluation and Implications of Serosal Involvement in Gastrointestinal Cancer 20. Ambrose NS, MacDonald F, Young J, Thompson H, Keighley MR (1989) Monoclonal antibody and cytological detection of free malignant cells in the peritoneal cavity during resection of colorectal cancer–can monoclonal antibodies do better? Eur J Surg Oncol 15:99–102 21. Yamamoto S, Akasu T, Fujita S, Moriya Y (2003).

Dissemination of gastric cancer and its potential as a novel marker for the detection of peritoneal micrometastases with real-time RT-PCR. Br J Cancer 90:665– 671 29. Bando E, Yonemura Y, Takeshita Y et al. (1999) Intraoperative lavage for cytological examination in 1, 297 patients with gastric carcinoma. Am J Surg 178:256– 262 30. Wu CC, Chen JT, Chang MC et al. (1997) Optimal surgical strategy for potentially curable serosa-involved gastric carcinoma with intraperitoneal free cancer cells. J Am Coll Surg 184:611–617 31.

The pathologist is therefore faced with some conflicting evidence when it comes to defin- Fig. 1 The histological classifi fication of serosal involvement according to the Gloucester, UK, series. There are tumour cells present at the serosal surface with an appropriate mesothelial reaction (LPI 3) but there are also tumour cell groups apparently free with the peritoneal cavity (LPI 4), in this case of colonic carcinoma with extensive local spread 3 Pathological Evaluation and Implications of Serosal Involvement in Gastrointestinal Cancer ing what is meant by true serosal involvement.

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