By Iwao Ojima, Gregory D. Vite, Karl-Heinz Altmann
content material: melanoma drug discovery and improvement : new paradigms for a brand new millennium / E.A. Sausville ... [et al.] --
Evolutionary biosynthesis of anticancer medicines / George R. Pettit --
a few contemporary advancements within the synthesis and structure-activity dating of novel taxanes / John F. Kadow ... [et al.] --
New new release taxoids and hybrids of microtubule-stabilizing anticancer brokers / Iwao Ojima ... [et al.] --
Discodermolide and taxol : a synergistic drug blend in human carcinoma phone strains / Susan Band Horwitz ... [et al.] --
hugely effective semisynthesis of biologically energetic epothilone derivatives / Gregory D. Vite ... [et al.] --
man made and semisynthetic analogs of epothilones : chemistry and organic job / Karl-Heinz Altmann ... [et al.] --
Synthesis and organic job of epothilones / Ulrich Klar ... [et al.] --
Epothilones and sarcodictyins : from combinatorial libraries to designed analogs / Nicolas Winssinger and K.C. Nicolaou --
Synthesis and structure-activity courting stories of cryptophycins : a unique type of effective antimitotic antitumor depsipeptides / Chuan Shih ... [et al.] --
Farnesyltransferase inhibitors as strength anticancer brokers / J.B. Gibbs ... [et al.] --
Farnesyltransferase inhibitors : from squalene synthase inhibitors to the scientific agent BMS-214662 / John T. Hunt --
Inhibiting farnesyl protein transferase with Sch-66336 : in all likelihood a selective noncytotoxic treatment for human melanoma / A.G. Taveras ... [et al.] --
Pyrrolo[2,3-d]pyrimidine and pyrazolo[3,4-d]pyrimidine derivatives as selective inhibitors of the EGF receptor tryosine kinase / G. Caravatti ... [et al.] --
STI571 : a brand new therapy modality for CML? / Jürg Zimmermann, Pascal Furet, and Elisabeth Buchdunger --
the invention and improvement of second-generation matrix metalloproteinase inhibitors for the therapy of melanoma / Andy Baxter and John Montana --
customers for antiangiogenic cures established upon VEGF inhibition / Pascal Furet and Paul W. Manley --
Carbohydrate-based tumor antigens as antitumor vaccine brokers / Jennifer R. Allen and Samuel J. Danishefsky --
medicinal drugs to reinforce the healing efficiency of anticancer antibodies : antibody-drug conjugates as tumor-activated prodrugs / Walter A. Blättler and Ravi V.J. Chari.
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